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Year : 1976  |  Volume : 8  |  Issue : 2  |  Page : 135-140

Effect of intravenous infusion of calcium chloride on sheep ECG

Correspondence Address:
B S Paul

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Source of Support: None, Conflict of Interest: None

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The effect of intravenous infusion of 6% calciumchloride on the E. C. G. of sheep, both during and after stopping the administration has been studied. There was significant increase in heart rate at serum calcium levels of 22.35Ort4.365 mg per cent and its intensity increased with the dose. The QT interval and ST segment were shortened significantly while the prolongation of PR interval and QRS complex was insignificant. The amplitudes of R and T waves were increased and it was significant only for the latter at swum calcium levels of 22.350(4.365 to 27.600(5.555 mg %. The infusion of calcium chloride also resulted in various types of arrhythmias viz. sinus arrhythmia with bradycardia and atrio-ventricular blocks.The animals showed laboured respiration and restlessness during infusion and showed tachycardia with disturbed rhythm of premature beats and atrio-ventricular blocks for 2-4 hours after stopping the infusion.There were also delayed deaths.


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