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Year : 1975  |  Volume : 7  |  Issue : 4  |  Page : 39-44

Effects of potassium on electrocardiographic and serum electrolyte changes induced by chlorpromazine and GO-3315 in experimental animals

Correspondence Address:
K C Kotia

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Source of Support: None, Conflict of Interest: None

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The present study incorporates the effects of potassium chloride on various electrocardiographic end serum electrolyte changes produced by chlorpromazine and GO-3315. Both the drugs when administered with potassium, increase the P R and Q R S interval while decrease the QT interval. Abnormal ventricular complexes do not occur when both the drugs are given with potassium in contrast t o the drugs when given alone. Both the drugs have insignificant affect on serum Na+, Cl- and Ca++ but decrease the serum K+ levels.


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