| RESEARCH PAPER
|Year : 1975 | Volume
| Issue : 4 | Page : 21-25
Screening of metal complexes for biological activity: Part I. Pharmacological investigations of some cobalt (II) oxalate complexes with substituted pyridines and quinoline.
SK Bajpai, PR Shukla
Same oxalatoamine cobalt (II) complexes of the general formula COC2O4 (am), nH20 were prepared with a view to study their pharmacological activities. Compounds No. 1. 3 and 4 showed depressant effect on CNS, whereas compounds No. 5 and 6 were stimulants. Compounds No. 1, 2. 3 and 5. however. Possessed weak anti-inflammatory activity, whereas compounds No. 2 and 4 exhibited pronounced antipassive cutaneous anaphylaxis activity, The compounds studied neither showed any significant effect on CVS nor did they exhibit anti-arrhythmic and diuretic activity.
S K Bajpai
Source of Support: None, Conflict of Interest: None