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Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 77-81

Effect of oxytocin on the prostaglandin induced responses of the intestine in the cat

Correspondence Address:
V N Puri

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Source of Support: None, Conflict of Interest: None

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Prostaglanding E1 and F2( induce a biphasic response characterized by an initial relaxation followed by contraction of the intestine in the cat. Pretreatment with oxytocin enhances the relaxant phase and inhibits the contractile phase significantly. It has been postulated that combined administration of prostaglandin and oxytoin may lessen the gastro-intestinal side effects of prostaglandin in the human.


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