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Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 51-57

A neuro-psychopharmacological study of Cannabis indica

Correspondence Address:
P P Singh

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Source of Support: None, Conflict of Interest: None

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Neuro-psychopharmacological studies have been conducted on the resin extracted from Cannabis indica on albino rats and mice. The resin was found to have hypothermic. Barbiturate hypnotic potentiating, analgesic, suppression of conditioned avoidance response and a mixed excitation-depression effects, similar to those reported for Cannabis sativa or THC. The resin was found to have anticonvulsant activity against metrazol and electroshock seizures and it also potentiated d-amphetamine toxicity in aggregated mice. The resin potentiated the analgesic activity of morphine and anticonvulsant activity of troxidone. In addition, the resin showed antipyretic and anti-inflammatory actions.


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