IPSIndian Journal of Pharmacology
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Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 44-50

Effects of some pharmacological agents on experimental convulsions in rats

Correspondence Address:
Bapat Veena

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Source of Support: None, Conflict of Interest: None

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Experimental convulsions were produced in rats by two methods : (i) injections of metrazol and (ii) audiogenic stimuli. The effects of various pharmacological agents which increase or decrease the levels of catecholamines or serotonin were studied by treating the animals with these agents prior to the experiment. It was found that those agents which raise the levels of catecholamines in preference to serotonin antagonize both the types of convulsions and vice versa.


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