IPSIndian Journal of Pharmacology
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 RESEARCH PAPER
Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 34-37

Studies on the mechanisms of toxic effects of procaine on CNS in mice



Correspondence Address:
V G Dhume


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Source of Support: None, Conflict of Interest: None


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Experiments performed on 398 albino mice indicate that norepinephrine, acetylcholine and 5- hydroxytryptamine are not involved in CNS toxicity of procaine. While caffeine increased the toxicity of procaine. pentobarbitone protected the mice against convulsions.






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