IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 151 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded169    
    Comments [Add]    

Recommend this journal


Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 24-33

Pharmacological actions of aqueous and alcoholic extracts of roots of Cichorium intibus, Linn

Correspondence Address:
M N Jindal

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Both the alcoholic and aqueous extracts of Cichorium Intibus (2OO-800 mg/kg, i. p.) exhibited anti-MES and anti-metrazole but limited antistrychnine activity. These extracts (2OO-800 mg/kg. i.p.) potentiated pentobarbitone and ethanol induced hypnosis in mice. exhibited analgesia [ED50 for alcoholic and aqueous extracts were 520 (505-541) and 480 (439-510) mg/kg, i. p. respectively], and potentiated morphine analgesia in rats. There was dose related antipyretic effect against LSD induced hyperpyrexia in rats. Cardio-vascular, smooth muscle and skeletal muscle actions appear to be cholinergic in nature. Both the extracts showed anti-inflammatory activity against formalin induced oedema. There is a considerable gap in between the pharmacodynamic and the toxic doses.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow