| RESEARCH PAPER
|Year : 1975 | Volume
| Issue : 3 | Page : 16-23
Electroencephalographic changes in rat during chronic administration of cannabis
VN Sharma, Singh Rameshwar, Krishna Veena
Cortical electroencephalographic activity (EEG) was studied in awake unanaesthetized rats after daily oral administration of cannabis plant power (Cannabis sativa) 50 mg/kg/day for 35 days. During the first 7-8 days this dose caused increase of both frequency and amplitude. and some spiking activity in the EEG. From 8-9th day onwards cannabis caused decrease in the frequency es well as in the amplitude of the EEG.
V N Sharma
Source of Support: None, Conflict of Interest: None