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Year : 1975  |  Volume : 7  |  Issue : 3  |  Page : 16-23

Electroencephalographic changes in rat during chronic administration of cannabis

Correspondence Address:
V N Sharma

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Source of Support: None, Conflict of Interest: None

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Cortical electroencephalographic activity (EEG) was studied in awake unanaesthetized rats after daily oral administration of cannabis plant power (Cannabis sativa) 50 mg/kg/day for 35 days. During the first 7-8 days this dose caused increase of both frequency and amplitude. and some spiking activity in the EEG. From 8-9th day onwards cannabis caused decrease in the frequency es well as in the amplitude of the EEG.


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