RESEARCH PAPER |
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| Year : 1975 | Volume
: 7
| Issue : 3 | Page : 24--33 |
Pharmacological actions of aqueous and alcoholic extracts of roots of Cichorium intibus, Linn
MN Jindal, VK Patel, NB Patel
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Correspondence Address:
M N Jindal
Both the alcoholic and aqueous extracts of Cichorium Intibus (2OO-800 mg/kg, i. p.) exhibited anti-MES and anti-metrazole but limited antistrychnine activity. These extracts (2OO-800 mg/kg. i.p.) potentiated pentobarbitone and ethanol induced hypnosis in mice. exhibited analgesia [ED50 for alcoholic and aqueous extracts were 520 (505-541) and 480 (439-510) mg/kg, i. p. respectively], and potentiated morphine analgesia in rats. There was dose related antipyretic effect against LSD induced hyperpyrexia in rats. Cardio-vascular, smooth muscle and skeletal muscle actions appear to be cholinergic in nature. Both the extracts showed anti-inflammatory activity against formalin induced oedema. There is a considerable gap in between the pharmacodynamic and the toxic doses.
How to cite this article:
Jindal M N, Patel V K, Patel N B. Pharmacological actions of aqueous and alcoholic extracts of roots of Cichorium intibus, Linn.Indian J Pharmacol 1975;7:24-33
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How to cite this URL:
Jindal M N, Patel V K, Patel N B. Pharmacological actions of aqueous and alcoholic extracts of roots of Cichorium intibus, Linn. Indian J Pharmacol [serial online] 1975 [cited 2013 Jun 20 ];7:24-33
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1975;volume=7;issue=3;spage=24;epage=33;aulast=Jindal;type=0 |
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