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 EDUCATION FORUM
Year : 2006  |  Volume : 38  |  Issue : 2  |  Page : 95-99

Exploring Indian medicinal plants for antiulcer activity


Division of Pharmacology, Central Drug Research Institute, Lucknow - 226 001, India

Correspondence Address:
Gautam Palit
Division of Pharmacology, Central Drug Research Institute, Lucknow - 226 001
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.24613

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Peptic ulcer disease (PUD) is a serious gastrointestinal disorder that requires a well targeted therapeutic strategy. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapses, side effects, and drug interactions. This has been the rationale for the development of new antiulcer drugs and the search for novel molecules has been extended to herbal drugs that offer better protection and decreased relapse. Drugs of plant origin are gaining popularity and are being investigated for a number of disorders, including peptic ulcer. The present article reviews the antiulcerogenic and ulcer healing property of Ocimum sanctum , Allophylus serratus , Desmodium gagenticum, Azadirachta indica , Hemidesmus racemosus , Asparagus racemosus, and Musa sapientum. We have highlighted some of the important plants reported for their anti-ulcer and ulcer healing properties, in our laboratory and elsewhere during the last few years. Ayurvedic knowledge supported by modern science is necessary to isolate, characterise, and standardise the active constituents from herbal sources for antiulcer activity.






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