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Year : 1976  |  Volume : 8  |  Issue : 4  |  Page : 235-239

Influence of diazepam on ventricular extra-systoles induced by noradrenaline in unanaesthetised dogs following coronary ligation


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Kuruvilla Alice


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Noradrenaline when injected into unanaesthetised dogs on third or fourth post-operative day follwing coronary ligation, induced extrasystoles. Pretreatment with diazepam reduced the number and percentage of these extrasystoles. A Similar effect was also observed when diarepam was given after extrasystoles were induced by noradrenaline. The results suggest that diarepam may be useful in controlling the ventricular extrasystoles associated with myocardial infarction.






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